As women age, energy levels often decline due to hormonal changes, stress, and nutritional deficiencies. If you frequently feel fatigued, sluggish, or mentally drained, the right supplements can help boost energy levels in women over 40, restore vitality and improve overall well-being. Fortunately, Amazon offers a variety of high-quality supplements specifically designed to combat fatigue and support sustained energy. In this blog, we’ll explore the top ten Amazon supplements that can help boost energy levels in women over 40, keeping you active and feeling your best.
1. B Vitamins – The Ultimate Energy Boosters
Best Pick on Amazon: Nature Made Super B-Complex with Vitamin C

Rating: 4.7/5 | Price: Affordable
Why It’s Essential
B vitamins (B12, B6, and folate) play a crucial role in energy metabolism by converting food into fuel. Many women over 40 experience B12 deficiencies, leading to fatigue, brain fog, and weakness.
Benefits:
- Supports metabolism and reduces fatigue
- Enhances brain function and mood
- Promotes healthy red blood cell production
How to Take It:
Take one tablet daily with a meal for optimal absorption.
2. Coenzyme Q10 (CoQ10) – The Cellular Energy Powerhouse
Best Pick on Amazon: Qunol Ultra CoQ10

Rating: 4.8/5 | Price: Moderate
Why It’s Essential
CoQ10 is a natural antioxidant that helps cells produce energy. As we age, our CoQ10 levels decline, leading to low energy, muscle weakness, and heart health concerns.
Benefits:
- Increases cellular energy production
- Supports heart health and circulation
- Reduces muscle fatigue and soreness
How to Take It:
Take one softgel daily with food for better absorption.
3. Iron – The Oxygen Transporter
Best Pick on Amazon: MegaFood Blood Builder

Rating: 4.7/5 | Price: Mid-range
Why It’s Essential
Iron is essential for oxygen transport in the blood. Women over 40, especially those experiencing perimenopause or heavy periods, may have low iron levels, leading to chronic fatigue, dizziness, and weakness.
Benefits:
- Prevents iron-deficiency anemia
- Supports better oxygen circulation
- Increases stamina and endurance
How to Take It:
Take one tablet daily with vitamin C-rich foods to enhance absorption.
4. Magnesium – The Stress & Energy Regulator
Best Pick on Amazon: Natural Vitality Calm Magnesium Powder

Rating: 4.6/5 | Price: Affordable
Why It’s Essential
Magnesium plays a key role in energy production, muscle relaxation, and stress reduction. A deficiency can cause fatigue, muscle cramps, and difficulty sleeping, which further drains energy.
Benefits:
- Reduces stress and anxiety
- Improves sleep for better energy levels
- Supports muscle and nerve function
How to Take It:
Mix one teaspoon in warm water before bed for relaxation and energy replenishment.
5. Ashwagandha – The Natural Adaptogen for Energy & Stress Relief
Best Pick on Amazon: NutriRise Organic Ashwagandha with Black Pepper

Rating: 4.7/5 | Price: Affordable
Why It’s Essential
Ashwagandha is an adaptogenic herb that helps balance stress hormones, boost energy, and reduce fatigue. It’s particularly beneficial for women over 40 experiencing hormonal imbalances and adrenal fatigue.
Benefits:
- Reduces stress and cortisol levels
- Improves stamina and mental clarity
- Supports hormonal balance
How to Take It:
Take two capsules daily for best results.
6. Rhodiola Rosea – The Fatigue Fighter
Best Pick on Amazon: Nootropics Depot Rhodiola Rosea Extract

Rating: 4.7/5 | Price: Mid-range
Why It’s Essential
Rhodiola Rosea is another powerful adaptogen that helps fight physical and mental fatigue, making it an excellent choice for women who feel drained throughout the day.
Benefits:
- Increases mental clarity and focus
- Reduces stress and burnout
- Boosts endurance and energy levels
How to Take It:
Take one capsule in the morning or early afternoon.
7. Omega-3 Fatty Acids – The Brain & Energy Booster
Best Pick on Amazon: Nordic Naturals Ultimate Omega

Rating: 4.8/5 | Price: Moderate
Why It’s Essential
Omega-3 fatty acids support brain function, heart health, and energy production, making them a must-have for women over 40.
Benefits:
- Improves cognitive function
- Supports heart and joint health
- Reduces inflammation that causes fatigue
How to Take It:
Take two softgels daily with food.
8. L-Carnitine – The Metabolism Booster
Best Pick on Amazon: NOW Sports L-Carnitine

Rating: 4.6/5 | Price: Affordable
Why It’s Essential
L-Carnitine is an amino acid that helps transport fat into cells for energy production, supporting both metabolism and stamina.
Benefits:
- Boosts metabolism and weight management
- Enhances physical performance and endurance
- Reduces muscle fatigue
How to Take It:
Take one capsule before exercise for best results.
9. Vitamin D – The Immunity & Energy Enhancer
Best Pick on Amazon: Sports Research Vitamin D3 with Coconut Oil

Rating: 4.8/5 | Price: Affordable
Why It’s Essential
Vitamin D deficiency is common in women over 40 and can lead to fatigue, mood swings, and muscle weakness.
Benefits:
- Supports immune function and bone health
- Reduces fatigue and improves mood
- Enhances muscle strength
How to Take It:
Take one softgel daily with a meal.
10. Maca Root – The Natural Hormone Balancer
Best Pick on Amazon: Viva Naturals Organic Maca Powder

Rating: 4.7/5 | Price: Mid-range
Why It’s Essential
Maca root helps balance hormones, improve stamina, and increase energy levels, making it especially useful for women in perimenopause or menopause.
Benefits:
- Boosts energy and stamina
- Supports hormonal balance
- Enhances libido and mood
How to Take It:
Mix one teaspoon into smoothies, coffee, or yogurt.
Final Thoughts
Feeling exhausted all the time isn’t normal, and the right supplements can make a significant difference in boosting energy, reducing stress, and improving overall well-being. Whether you need more B vitamins for metabolism, CoQ10 for cellular energy, or Ashwagandha for stress relief, these Amazon bestsellers can help you boost energy levels in women over 40 and regain vitality.
Disclaimer
This article is for informational purposes only and is not intended as medical advice. Consult a healthcare professional before starting any new supplement, especially if you have underlying health conditions, are pregnant, or are taking medications. Holistik Fitness may earn commissions from qualifying purchases through affiliate links.